2022| 2021| 2020| 2019| 2018| 2017| 2016| 2015| 2014| 2013| 2012| 2010| 2008| 2007| 2006| 2005| 2004
2024
versatile “one-fits-all" system to acutely deplete RNA binding proteins from condensates.
J. Cell Biol. 2024 Vol. 223 No. 2 e202304030. DOI: https://doi.org/10.1083/jcb.202304030
2023
de Oliveira Freitas Machado C, Schafranek M, Brüggemann M, Hernández Cañás MC, Keller M, Di Liddo A, Brezski A, Blümel N, Arnold B, Bremm A, Wittig I, Jaé N, McNicoll F, Dimmeler S, Zarnack K, Müller-McNicoll M. Nucleic Acids Res. 2023 Jan 25;51(2):870-890. doi: 10.1093/nar/gkac1225. PMID: 36620874
2022
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm.
Kirchhof L, Fouani Y, Knau A, Aslan GS, Heumüller AW, Wittig I, Müller-McNicoll M, Dimmeler S, Jaé N. Noncoding RNA. 2022 Jun 30;8(4):49. doi: 10.3390/ncrna8040049. PMID: 35893232
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A. Nucleic Acids Res. 2022 Mar 31:gkac212. doi: 10.1093/nar/gkac212. Online ahead of print. PMID: 35357505
Exploring the multifunctionality of
SR proteins.
Slišković I, Eich H, Müller-McNicoll M. Biochem Soc Trans. 2021 Dec 23:BST20210325.
doi: 10.1042/BST20210325.
SUMO: Glue or Solvent for
Phase-Separated Ribonucleoprotein Complexes and Molecular Condensates?
Keiten-Schmitz
J, Röder L, Hornstein E, Müller-McNicoll M, Müller S. Front Mol Biosci.
2021 May 7;8:673038. doi: 10.3389/fmolb.2021.673038.
The SRSF4-GAS5-Glucocorticoid
Receptor Axis Regulates Ventricular Hypertrophy.
Larrasa-Alonso J, Villalba-Orero M, Martí-Gómez C, Ortiz-Sánchez P,
López-Olañeta MM, Rey-Martín MA, Sánchez-Cabo F, McNicoll F, Müller-McNicoll
M, García-Pavía P, Lara-Pezzi E. Circ Res. 2021 Sep 3;129(6):669-683. doi:
10.1161/CIRCRESAHA.120.318577.
SRSF3 and SRSF7 modulate 3'UTR
length through suppression or activation of proximal polyadenylation sites and
regulation of CFIm levels
Oliver Daniel Schwich, Nicole Blümel, Mario
Keller, Marius Wegener, Samarth Thonta Setty, Melinda Elaine Brunstein,
Ina Poser , Igor Ruiz De Los Mozos, Beatrix Suess, Christian Münch, François
McNicoll, Kathi Zarnack, Michaela Müller-McNicoll
Genome Biol. 2021 Mar 11;22(1):82.doi: 10.1186/s13059-021-02298-y
A paralog-specific role of COPI
vesicles in the neuronal differentiation of mouse pluripotent cells
Manu Jain Goyal, Xiyan Zhao, Mariya Bozhinova, Karla Andrade-López, Cecilia
de Heus, Sandra Schulze-Dramac, Michaela Müller-McNicoll, Judith
Klumperman, Julien Béthune
Life Sci Alliance. 2020 Jul 14;3(9):e202000714.doi: 10.26508/lsa.202000714
SRSF7 maintains its homeostasis
through the expression of Split-ORFs and nuclear body assembly.
Vanessa Königs, Camila de Oliveira Freitas Machado, Benjamin Arnold,
Nicole Blümel, Anfisa Solovyeva, Sinah Löbbert, Michal Schafranek,
Igor Ruiz De Los Mozos, Ilka Wittig, Francois McNicoll, Marcel H. Schulz
& Michaela Müller-McNicoll
Nat Struct Mol Biol. 2020 Mar;27(3):260-273. doi: 10.1038/s41594-020-0385-9
View from an mRNP: The Roles of SR
Proteins in Assembly, Maturation and Turnover.
Marius
Wegener & Michaela Müller-McNicoll
Adv Exp Med Biol. 2019;1203:83-112. doi: 10.1007/978-3-030-31434-7_3
A combined computational pipeline to
detect circular RNAs in human cancer cells under hypoxic stress.
Antonella Di Liddo, Camila de Oliveira Freitas Machado, Sandra
Fischer, Stefanie Ebersberger, Andreas W Heumüller, Julia E Weigand, Michaela
Müller-McNicoll, Kathi Zarnack
J Mol Cell Biol. 2019 Sep 27. pii: mjz094. doi: 10.1093/jmcb/mjz094
Long and Repeat-Rich Intronic
Sequences Favor Circular RNA Formation under Conditions of Reduced Spliceosome
Activity.
Mantian
Wang, Jingyi Hou, Michaela Müller-McNicoll, Wei Chen, Erin M.Schuman
iScience. 2019 Oct 25;20:237-247. doi: 10.1016/j.isci.2019.08.058
The lncRNA Locus
Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse
Development
Nicole Ritter, Tamer Ali, Nina Kopitchinski,
Peggy Schuster, Arica Beisaw, David A. Hendrix, Marcel H. Schulz, Michaela
Müller-McNicoll, Stefanie Dimmeler, Phillip Grote
Dev Cell. 2019 Aug 12. doi:10.1016/j.devcel.2019.07.013
Auto-regulatory feedback
by RNA-binding proteins.
Müller-McNicoll M, Rossbach O, Hui J, Medenbach J.
J Mol Cell Biol. 2019 Jun 1. pii: mjz043. doi: 10.1093/jmcb/mjz043
Loss of SRSF3 in
Cardiomyocytes Leads to Decapping of Contraction Related mRNAs and Severe
Systolic Dysfunction.
Ortiz-Sánchez
P, Villalba-Orero M, López-Olañeta MM, Larrasa-Alonso J, Sanchez-Cabo F,
Martí-Gómez C, Camafeita E, Gomez-Salinero JM, Ramos-Hernández L, Nielsen PJ,
Vazquez J, Müller-McNicoll M, Garcia-Pavia P, Lara-Pezzi E.
Circ Res. 2019 May 30. doi: 10.1161/CIRCRESAHA.118.314515
Splicing of long non-coding RNAs
primarily depends on polypyrimidine tract and 5′ splice-site sequences due to
weak interactions with SR proteins
Krchnáková Z, Thakur PK, Krausová M, Bieberstein
N, Haberman N, Müller-McNicoll M, Stanek D.
Nucleic Acids Research, Volume 47, Issue 2, 25 January 2019, Pages 911–928,
https://doi.org/10.1093/nar/gky1147
Characterization of
cis-acting elements that control oscillating alternative splicing
Gesine Goldammer, Alexander Neumann, Miriam
Strauch, Michaela Müller-Mcnicoll, Florian Heyd & Marco Preußner
RNA Biol. 2018 Sep 10:1-12. doi: 10.1080/15476286.2018.1502587. [Epub ahead of
print]
A Quantitative Heterokaryon Assay to Measure the
Nucleocytoplasmic Shuttling of Proteins
François McNicoll, Michaela
Müller-McNicoll
bio-protocol. 2018 Sep 05. doi: DOI:10.21769/BioProtoc.2472
High-Throughput Screens for
cis-Acting RNA Sequence Elements That Promote Nuclear Retention.
Zarnack K, Müller-McNicoll M.
Biochemistry. 2018 May 24. doi: 10.1021/acs.biochem.8b00479. [Epub ahead of print] No abstract
available
Nuclear retention of mRNAs - quality
control, gene regulation and disease
Wegener M, Müller-McNicoll M
Semin Cell Dev Biol. 2017 Nov 1. pii: S1084-9521(17)30442-1. doi:
10.1016/j.semcdb.2017.11.001
Fractionation iCLIP detects
persistent SR protein binding to conserved, retained introns in chromatin,
nucleoplasm and cytoplasm
Brugiolo M, Botti V, Liu N, Müller-McNicoll M, Neugebauer KM
Nucleic Acids Research, PMID: 28977534 DOI: 10.1093/nar/gkx671
TGFβ/SMAD signalling
modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation
Saul MJ, Groher F, Hegewald AB, Müller-McNicoll M, Marschalek
R, Suess B, Steinhilber
Prostaglandins & Other Lipid Mediators, 2017, PMID: 28803964
doi: 10.1016/j.prostaglandins.2017.07.006
RNA secondary structure
and nucleotide composition of the conserved hallmark sequence of Leishmania
SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA
degradation
Hiva Azizi, Tatiany P. Romão, Karen Santos Charret, Prasad K. Padmanabhan,
Osvaldo P. de Melo Neto, Michaela Müller-McNicoll, Barbara Papadopoulou
PLOS One, July 13, 2017, doi:https://doi.org/10.1371/journal.pone.0180678
Body Temperature Cycles
Control Rhythmic Alternative Splicing in Mammals
Marco Preußner, Gesine Goldammer, Alexander Neumann, Tom
Haltenhof, Pia Rautenstrauch, Michaela Müller-McNicoll,Florian
Heyd
Molecular Cell , Volume 67 , Issue 3 , 433 - 446.e4, doi: http://dx.doi.org/10.1016/j.molcel.2017.06.006
Cellular differentiation state
modulates the mRNA export activity of SR proteins
Botti V, McNicoll F, Steiner MC, Richter FM, Solovyeva A, Wegener
M, Schwich OD, Poser I, Zarnack K, Wittig I, Neugebauer KM, Müller-McNicoll
M
J Cell Biol. 2017 Jun 7. pii: jcb.201610051. doi: 10.1083/jcb.201610051
SIDER2 retroposon-mediated mRNA
decay in Leishmania is coupled to translation
Azizi H, Müller-McNicoll M, Papadopoulou B
J. MBio. 2017 Jan 31;8(1). pii: e02288-16. doi: 10.1128/mBio.02288-16.
Differential Binding of
Mitochondrial Transcripts by MRB8170 and MRB4160 Regulates Distinct Editing
Fates of Mitochondrial mRNA in Trypanosomes
Dixit S, Müller-McNicoll M, David V, Zarnack K, Ule J, Hashimi H, Lukeš
J. MBio. 2017 Jan 31;8(1). pii: e02288-16. doi: 10.1128/mBio.02288-16.
SR proteins are NXF1 adaptors that link alternative RNA
processing to mRNA export
Michaela Müller-McNicoll, Valentina Botti, Antonio M. de Jesus
Domingues, Holger Brandl, Oliver D. Schwich, Michaela C. Steiner, Tomaz
Curk, Ina Poser, Kathi Zarnack, and Karla M. Neugebauer
Genes &
Dev. 2016. 30: 553-566, doi:10.1101/gad.276477.115
Approaches for Studying
mRNA Decay Mediated by SIDER2 Retroposons in Leishmania
Barbara Papadopoulou, Michela Müller-McNicoll, Prasad K.
Padmanabhan
DOI: 10.1007/978-1-4939-1438-8_7
In book: Methods in Molecular Biology, Vol. 1201 Parasites Genomic Protocols,
Chapter: Approaches for Studying mRNA Decay Mediated by SIDER2 Retroposons in
Leishmania, Publisher: Springer, Editors: Christopher Peacock
Good cap/bad cap: how the
cap-binding complex determines RNA fate.
Müller-McNicoll
M, Neugebauer
KM
Nat Struct Mol Biol. 2014 Jan;21(1):9-12. doi: 10.1038/nsmb.2751.
How cells get the message: dynamic
assembly and function of mRNA-protein complexes.
Müller-McNicoll
M, Neugebauer
KM.
Nat Rev Genet. 2013 Apr;14(4):275-87. doi:
10.1038/nrg3434. Epub 2013 Mar 12.
The RNA-binding landscapes of two SR
proteins reveal unique functions and binding to diverse RNA classes.
Änkö
ML, Müller-McNicoll M, Brandl H, Curk T, Gorup
C, Henry I, Ule J, Neugebauer KM.
Genome Biol. 2012;13(3):R17. doi: 10.1186/gb-2012-13-3-r17.
mRNA: a complex(ed) life.
Müller M, Neugebauer KM, Eckmann
C.
Genome Biol. 2010;11(5):304. doi:
10.1186/gb-2010-11-5-304. Epub 2010 May 25.
Rapid decay of unstable Leishmania
mRNAs bearing a conserved retroposon signature 3'-UTR motif is initiated by a
site-specific endonucleolytic cleavage without prior deadenylation.
Müller M, Padmanabhan PK, Rochette A, Mukherjee
D, Smith M, Dumas C, Papadopoulou B.
Nucleic Acids Res. 2010 Sep;38(17):5867-83. doi: 10.1093/nar/gkq349. Epub
2010 May 7.
Selective inactivation of SIDER2
retroposon-mediated mRNA decay contributes to stage- and species-specific gene
expression in Leishmania.
Müller M, Padmanabhan PK, Papadopoulou B.
Mol Microbiol. 2010 Jul;77(2):471-91.
doi: 10.1111/j.1365-2958.2010.07226.x. Epub 2010 May 24.
Stage-specific expression of the
glycine cleavage complex subunits in Leishmania infantum.
Müller M, Papadopoulou B.
Mol Biochem Parasitol. 2010 Mar;170(1):17-27. doi:
10.1016/j.molbiopara.2009.11.009. Epub 2009 Dec 2.
Identification of geographically
distributed sub-populations of Leishmania (Leishmania) major by microsatellite
analysis.
Al-Jawabreh
A, Diezmann S, Müller M, Wirth T, Schnur
LF, Strelkova MV, Kovalenko DA, Razakov SA, Schwenkenbecher
J, Kuhls K, Schönian G.
BMC Evol Biol. 2008 Jun 24;8:183. doi: 10.1186/1471-2148-8-183.
Regulation of Gene Expression in Leishmania Throughout
a Complex Digenetic Life Cycle
Barbara Papadopoulou, Michaela Müller, Annie Rochette,
Francois McNicoll,Carole Dumas, Conan Chow
In book: Leishmania: After the Genome, Chapter: Regulation of Gene Expression
in Leishmania Throughout a Complex Digenetic Life Cycle, Publisher: Horizon
Scientific Press, Editors: Peter J Myler & Nicolas Fasel, pp.29-54
Members of a large retroposon family
are determinants of post-transcriptional gene expression in Leishmania.
Bringaud F, Müller M, Cerqueira GC, Smith
M, Rochette A, El-Sayed NM, Papadopoulou B, Ghedin E.
PLoS
Pathog. 2007 Sep 7;3(9):1291-307.
A novel class of developmentally
regulated noncoding RNAs in Leishmania.
Dumas C, Chow C, Müller M, Papadopoulou B.
Eukaryot Cell. 2006 Dec;5(12):2033-46. Epub 2006 Oct 27.
A combined proteomic and
transcriptomic approach to the study of stage differentiation in Leishmania
infantum.
McNicoll F, Drummelsmith J, Müller M, Madore
E, Boilard N, Ouellette M, Papadopoulou B.
Proteomics. 2006
Jun;6(12):3567-81.
Distinct 3'-untranslated region
elements regulate stage-specific mRNA accumulation and translation in
Leishmania.
McNicoll F, Müller M, Cloutier S, Boilard
N, Rochette A, Dubé M, Papadopoulou B.
J Biol
Chem. 2005 Oct 21;280(42):35238-46. Epub 2005 Aug 22.
A coding mutation within
the first exon of the human MD-2 gene results in decreased
lipopolysaccharide-induced signaling.
Hamann
L, Kumpf O, Müller M, Visintin A, Eckert
J, Schlag PM, Schumann RR.
Genes Immun. 2004 Jun;5(4):283-8.
de Oliveira Freitas Machado C, Schafranek M, Brüggemann M, Hernández Cañás MC, Keller M, Di Liddo A, Brezski A, Blümel N, Arnold B, Bremm A, Wittig I, Jaé N, McNicoll F, Dimmeler S, Zarnack K, Müller-McNicoll M. Nucleic Acids Res. 2023 Jan 25;51(2):870-890. doi: 10.1093/nar/gkac1225. PMID: 36620874
Arbeitskreis RNA Regulation in Higher Eukaryotes
Institut für Molekulare Biowissenschaften
Prof. Michaela Müller-McNicoll, PhD
Biologicum, Campus Riedberg
Gebäudeteil B, 1.OG
Max-von-Laue-Straße 13
60438 Frankfurt am Main
T +49 69 798 - 42079
Mueller-McNicoll(at)bio.uni-frankfurt.de
Sprechzeiten:
Donnerstags, 13-14 Uhr 13-14 Uhr nur nach Vereinbarung. Mindestens eine Woche im Voraus anSekretariat:
Frau Baechle Jourdan
office-muellermcnicoll@bio.uni-frankfurt.de